The uterus may naturally lie in different positions such as anteverted/retroverted, anteflexed/retroflexed, or midline, and it may be rotated (especially during pregnancy). It is further supported (inferiorly) by the pelvic diaphragm, urogenital diaphragm, and perineal body. Several ligaments support the uterus, including the utero-ovarian ligament, round ligament, broad ligament, cardinal ligament, and uterosacral ligaments. The female uterus subdivides into four main anatomic segments (from superior to inferior): the fundus a broad curved area in which fallopian tubes connects to the uterus, corpus (body) the main part of a uterus, and it starts directly below the level of fallopian tubes and continues downward, isthmus a lower neck region of the uterus, and cervix which extends downwards from the isthmus and opens in the vagina.

Anatomically, the uterus is located in the female pelvis immediately posterior to the bladder and anterior to the rectum. Sometimes the development in utero may be incomplete this is called a Mullerian anomaly and can lead to many variants, ranging from a uterine septum to uterine didelphys (double uterus). On a coronal cut section, its cavity has an inverted triangle shape. The uterus is a hollow, pear-shaped organ that is responsible for a variety of functions such as gestation (pregnancy), menstruation, and labor and delivery.

Uterus shifted to the left